What is Advanced PRP / GFC Growth Factor Concentrate?
In the context of skin rejuvenation treatments, growth factor concentrate in the blood is relevant in procedures such as platelet-rich plasma (PRP) therapy or autologous growth factor concentrate therapy. Advanced PRP therapy / GFC involves extracting a sample of the patient's blood and processing it to concentrate the platelets, which contain a variety of growth factors. Platelets are rich in growth factors such as platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), vascular endothelial growth factor (VEGF), and epidermal growth factor (EGF), among others.
- Processing: After a blood sample is collected from a patient, it undergoes centrifugation to separate the platelet-rich plasma from other blood components. The resulting PRP contains a higher concentration of platelets and growth factors compared to whole blood this is known as growth factor concentrate.
- Application: The GFC is then applied topically or injected into the skin, typically in areas requiring rejuvenation or improvement. When applied to the skin, growth factors within the PRP can stimulate cellular processes involved in tissue repair, regeneration, and rejuvenation.
- Mechanism of Action: Once applied to the skin, the growth factors interact with cell surface receptors, initiating signaling cascades that promote collagen synthesis, angiogenesis (formation of new blood vessels), and the migration of fibroblasts and keratinocytes. This can lead to improved skin texture, increased skin thickness, reduced fine lines and wrinkles, and enhanced overall skin appearance.
- Effects: The growth factors help to revitalize aging or damaged skin by promoting the production of collagen and elastin fibers, which are essential for maintaining skin elasticity and firmness. Additionally, they can enhance skin hydration, improve skin tone and texture, and reduce the appearance of scars and pigmentation irregularities.
By leveraging the regenerative potential of growth factors, GFC therapy offers a non-surgical and minimally invasive option for improving skin quality and restoring a more youthful appearance.
- GFC is a Growth Factor Concentrate, a pure, highly safe & concentrated Growth Factor preparation that is engineered from a person's blood for superior results in Facial Rejuvenation.
- Various growth factors are stored in platelets (type of cells in our blood). Growth Factor Concentrate (GFC) in specially designed for various facial conditions like Facial rejuvenation, acne scars & Melasma/ Hyperpigmentation.
- Once GFC is injected into the skin it delivers the person's own growth factors at high concentration right in the layers of the skin. This results in stimulation of skin layer and subsequently leads to regeneration and repair.
Why Growth Factor Concentration GFC therapy?
- Highly effective: High concentration of growth factors promotes naturally & enhances damaged tissue regeneration for Facial rejuvenation, acne scars & Melasma / Hyperpigmentation
- Safe Highly: Safe as prepared from a person's blood unlike artificial toxin
- Quality: 1) Non-Pyrogenic (No contamination) 2) Zero RBCs and WBCs (WBCs & RBCs are risk for pain & inflammation)
- Convenience: 1) Lunchtime procedure 2) Easy, rapid and consistent GFC preparation

How GFC Therapy Works In Skin Rejuvenation?
- GFC Therapy extracts a high concentration of various kinds of growth factors from the blood
- GFC helps in the rapid, efficient, and thorough repair of the skin layer
- It also improves the skin quality and texture
- Thus, it makes the skin tighten and feel youthful
- GFC therapy can be used to enhance laser procedure and along with derma rollers for faster and improved rejuvenation
How GFC therapy work in Acne Scars?
- Scars left behind after acne breakouts can lead to reduced quality of life. A person may experience anxiety, lack of self-confidence, embarrassment, stress and impaired social contact.
- High concentration of various growth factors present in GFC triggers the enhanced natural healing process of the skin leading to smoothness of the scars.
- It can be combined with microneedling, needling, subscision, scar excision & other treatment modalities if required by doctor based on your condition
How GFC Therapy Works in Hyperpigmentation (Dark Spots) & Melasma?
- It can be GFC Therapy, through its various growth factors, lessens the process of melanin production.
- It can be It enhances the function of blood vessels and dermal elasticity, to promote skin regeneration and rejuvenation
- It can be as per your case, your doctor may also combine it with other treatments for better results.
Who are the best candidates for GFC Therapy?
- It can be GFC Therapy can be used by anyone, man or woman, who wants a blemish-free, rejuvenated skin.
- It can be It is most suitable for patients who don't want any synthetic filler or any synthetic chemicals/toxic/drugs.
What are the directions for use?
- It can be Though a total of 3 sessions, one per month is the most commonly recommended session plan, the actual number depends upon your conditions judged by your doctor.
Are there any restrictions after GFC Therapy?
- No shower/activities that will cause you to perspire for at least 8 hours
- No sunbathing for at least 48 hours after the treatment
- No scratching or rubbing face for 6 hours after the treatment
- Stay away from dust/polluted environment for a day
- Side effects like mild inflammation, redness, swelling & pain may subside in a few hours to a few days.
Why Do I Need Such A Procedure?
- With age and lifestyle issues, our skin functions start declining over time along with external damage caused by sun exposure, smoking, stress levels, and chemical/cosmetic exposures Such factors lead to problems like wrinkles, folds, fine lines, laugh lines, sagging lines, creepy lines, dryness, etc. With the advancement of science and technology, you can undo such problems to a large extent and reclaim back your image and confidence!
Growth Factor Concentrate (GFC )for face and skin treatments is available at ASPEN Clinic, NIBM Road, Pune by Dr Hina Khan.
Read More-
Botox – Anti Wrinkle Treatment | Dr. Hina Khan
Fillers For Face | Dr. Hina Khan